BDBM11333 Hydroxamate 14::N-hydroxy-2-[(2,3,4,5,6-pentafluorobenzene)sulfonamido]propanamide

SMILES CC(NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)NO

InChI Key InChIKey=AUIKJLRMPLDORG-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11333   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11333(Hydroxamate 14 | N-hydroxy-2-[(2,3,4,5,6-pentafluo...)
Affinity DataKi:  40nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universita Degli Studi

LigandPNGBDBM11333(Hydroxamate 14 | N-hydroxy-2-[(2,3,4,5,6-pentafluo...)
Affinity DataKi:  40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed